The Best CoQ10 and Ubiquinol Supplements
Updated By the HealthWorld editorial teamHow we pick
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Top picks at a glance
- 1

CoQ10 is a compound your cells use to produce energy, and the body's levels naturally decline with age. Ubiquinol is its active, reduced form, while regular CoQ10 (ubiquinone) is converted to it in the body. Qunol Ubiquinol 100 mg is our pick; it's the only CoQ10 product we currently list, so use the checklist below if you're comparing others.
Our picks

#1Best overall
Qunol Ubiquinol 100 mg
100 mg of ubiquinol, the active form of CoQ10, in one easy softgel a day.
What to look for
- Ubiquinol or ubiquinone
- Ubiquinol usually costs more; ubiquinone (labeled simply as CoQ10) is cheaper and is the form used in most studies. Some research suggests ubiquinol is absorbed better, particularly in older adults, but the evidence is mixed.
- Dose
- Common supplement doses are 100–200 mg a day. CoQ10 is fat-soluble, so take it with a meal that contains some fat.
- Softgels
- CoQ10 is generally absorbed better from oil-based softgels than from dry tablets or powders.
- Medication interactions
- CoQ10 may reduce the effect of warfarin and can lower blood pressure. If you take blood thinners, blood pressure or diabetes medication, talk to your doctor first.
Frequently asked questions
Can you take CoQ10 with statins?
Generally yes, and many statin users do. Statins lower the body's CoQ10 levels, which is why the supplement is popular with statin users, though studies on whether it eases statin-related muscle aches are mixed. Talk to your doctor before starting, especially if you also take blood thinners.
Ubiquinol or CoQ10: which is better?
Both raise CoQ10 levels in the blood. Ubiquinol is the active form and may be absorbed better by some people, especially older adults, but it costs more. Regular CoQ10 taken with a meal that contains fat works well for many people.
Is CoQ10 different for women?
No. The same forms and doses apply to women and men. If you're pregnant, breastfeeding or trying to conceive, talk to your doctor before taking CoQ10.
Sources
- Omega-3 Fatty Acids — Fact Sheet for Health Professionals — NIH Office of Dietary Supplements
- Coenzyme Q10 — NIH National Center for Complementary and Integrative Health
- Dietary Supplements — U.S. Food & Drug Administration