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Best Protein Shakes for Weight Loss (and GLP-1 Users)

Updated By the HealthWorld editorial teamHow we pick

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Top picks at a glance

  1. 1
    Premier Protein Protein Shake

    Best overall

    Premier Protein Protein Shake

    Protein 30 g · Calories 160

The best protein shakes for weight loss give you a lot of protein for few calories and little sugar, so they keep you full without crowding out real meals. Premier Protein is our pick, with 30 g of protein, 160 calories and 1 g of sugar per shake. It's the only ready-to-drink shake we currently list, so the checklist below will help you judge alternatives.

Our picks

  1. Premier Protein Protein Shake

    #1Best overall

    Premier Protein Protein Shake

    30 g of protein, 160 calories and 1 g of sugar per shake, plus 24 vitamins and minerals. Shelf-stable cartons are easy to keep at your desk or in a bag.

    Protein 30 gCalories 160Amazon Full facts →
Amazon's live top 100 in Protein

What to look for

Protein for the calories
Look for at least 20 g of protein in a shake that stays modest in calories. That combination is what makes a shake filling without adding much to your day.
Sugar and sweeteners
Choose shakes with little sugar. Most low-sugar shakes use sucralose or other sweeteners instead, so check the label if you avoid them.
Protein source
Milk protein and whey are complete proteins and the most common in ready-to-drink shakes. If you're dairy-free, look for a plant-based shake.
Replace, don't add
A shake helps weight loss when it replaces a snack or a higher-calorie meal, not when it's added on top of your usual eating.
If you take a GLP-1 medication
When appetite drops, doctors and dietitians often advise prioritizing protein to help preserve muscle. A protein-dense shake can help on low-appetite days; ask your care team how much protein you need.

Frequently asked questions

Are protein shakes good for weight loss?

They can help, because protein is filling and a ready-made shake is an easy swap for a less filling snack. They only work within an overall calorie deficit, and whole foods should still make up most of your diet.

What is the best protein shake for GLP-1 users?

Look for plenty of protein in a small volume and little sugar, since appetite is often low and large portions can feel uncomfortable. Premier Protein's 30 g of protein in one carton is a popular choice. Your prescriber or dietitian can tell you how much protein to aim for.

Are protein shakes OK for people with diabetes?

Low-sugar shakes can fit a diabetes eating plan, but check total carbohydrates as well as sugar, and watch how your blood sugar responds. If you take insulin or other glucose-lowering medication, talk to your doctor or dietitian before using shakes as meal replacements.

Can you take protein shakes or powder on a plane?

In the US, the TSA treats ready-to-drink shakes as liquids, so containers over 3.4 oz (100 ml) need to go in checked luggage. Protein powder is allowed in carry-ons, but containers over 12 oz (350 ml) may need extra screening, so single-serve packets are easier. Rules differ by country, so check before you fly.

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